Association of Hematological Parameters with Malaria Positive Patients in District Bannu

Abstract

Background: Malaria is one of the most widespread parasitic blood infections caused by plasmodium parasite. Well known feature of malaria is change in hematological parameters such as red blood cell, hemoglobin, platelets, white blood cell and differential count are significantly low. This study aim was to find the association of malaria with Complete Blood Count in malaria positive patient.

Methods: A six-month cross-sectional research was carried out in the Bannu district. Venous blood samples from 500 individuals were taken and placed in EDTA tubes for smear preparation and total blood counts. The Sysmex Hematology Analyzer was used to evaluate blood counts. Using SPSS-22, all data were calculated.

Results: Among total, 60 Malaria positive patient samples were processed for association of malaria with CBC. Out of total, male were 78% and female were 22%. Malaria positive patient with anaemia were found 53% in which male and female were 81% and 18% respectively. Thrombocytopenia were found in 16% in which male were 60% and 40% female patients. Malaria positive with abnormal TLC were observed in 11% patients (male 8%, female 3%). Moreover, Malaria positive with abnormal DLC were found 70% (male 73%, female 26%).

Conclusion: This study shows a significant change in hematological parameter in Malaria patients. Thrombocytopenia is second most common hematological abnormality. In TLC abnormality, rare cases of leukocytosis were noted. In malaria-endemic regions, hematological indicators may be a suitable and reliable adjuvant in the early identification of individuals with mild-to-severe parasitemia.