Bacteriophage therapy: An introduction and revitalized therapy for Klebsiella spp and Pseudomonas aeruginosa infections

Abstract

We are living in a microbial world and microbes like bacteria are affecting our lives in positive and also negative ways they are commensals in our bodies they play key roles in sustaining our environments and they are causing diseases. Bacteriophage therapy once considered a promising alternative to antibiotics is now being revitalized as a potential treatment for infections caused by Klebsiella spp and Pseudomonas aeruginosa. In recent years the rise of multidrug-resistant bacteria has become a major concern in healthcare settings. Antibiotic-resistant bacterial strains have emerged as a result of antibiotic abuse making it more and more difficult to treat illnesses. Bacteriophages that specifically target and infect bacteria offer a potential solution to combat these drug-resistant infections. This review article provides an introduction to bacteriophage therapy and highlights its potential use in treating infections caused by Klebsiella spp and Pseudomonas aeruginosa. The article addresses the urgent need for alternative strategies to antibiotics and explores the use of bacteriophages as biocontrol agents.